|
KMID : 0191120130280060908
|
|
Journal of Korean Medical Science
2013 Volume.28 No. 6 p.908 ~ p.914
|
|
|
Risk Factors for Acute Hepatitis A Infection in Korea in 2007 and 2009: A Case-Control Study
|
|
Seo Joo-Youn
Choi Bo-Youl
Ki Mo-Ran
Jang Hye-Lim
Park Hee-Suk
Son Hyun-Jin
Bae Si-Hyun
Kang Jin-Han
Jun Dae-Won
Lee Jin-Woo
Hong Young-Jin
Kim Young-Seok
Kim Chang-Hwi
Chang U-Im
Kim Jong-Hyun
Yang Hyeon-Woong
Kim Hong-Soo
Park Kyeong-Bae
Hwang Jae-Seok
Heo Jeong
Kim In-Hee
Kim Jung-Soo
Cheon Gab-Jin
|
|
|
Abstract
|
|
|
|
This study aimed to identify the risk factors associated with acute hepatitis A virus (HAV) infection in the Korean population. Participants were recruited from five referral hospitals across the country in 2007 and from 11 hospitals in 2009. Patients with positive anti-HAV IgM antibody tests became the case group, while patients treated for non-contagious diseases at the same hospitals were recruited as controls. A total of 222 and 548 case-control pairs were studied in the 2007 and 2009 surveys, respectively. Data from the surveys were analyzed jointly. In a multivariate analysis, sharing the household with HAV-infected family members (OR, 6.32; 95% CI, 1.4-29.6), contact with other HAV-infected individuals (OR, 4.73; 95% CI, 2.4-9.4), overseas travel in 2007 (OR, 19.93; 95% CI, 2.3-174.4), consumption of raw shellfish (OR, 2.51; 95% CI, 1.8-3.5), drinking bottled water (OR, 1.64; 95% CI, 1.3-8.4), and occupation that involve handling food (OR, 3.30; 95% CI, 1.3-8.4) increased the risk of HAV infection. Avoiding contact with HAV-infected individuals and avoiding raw foods eating could help minimize the risk of hepatitis A infection. Immunization must be beneficial to individuals who handle food ingredients occupationally or travel overseas to HAV-endemic areas.
|
|
|
KEYWORD
|
|
|
Case-Control Studies, Hepatitis A, Korea, Risk Factors
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
    
|
|